对高粘度玻璃离子体水泥的评估,该水泥被树提取物加载的半孔性二氧化纳米颗粒修饰:体外研究研究
Mai Samy Sheta1, Zienab E Eldin2
1Dental Biomaterials Department, Faculty of Dentistry, Tanta University, El-Giesh St., Tanta, Gharbia, Egypt. mai_sheta@dent.tanta.edu.eg.
Odontology
|January 20, 2026
概括
在高粘度玻璃离子体水泥 (HVGIC) 中添加树提取物加载的半孔性二氧化纳米颗粒 (EE@MSNs) 提高了机械强度和抗菌活性. 1%和3%的EE@MSNs得到了最佳结果,增强了牙水泥的性能.
科学领域:
- 牙科材料科学 牙科材料科学
- 在牙科的纳米技术.
- 生物材料工程 生物材料工程
背景情况:
- 玻璃离子体水泥 (GICs) 具有有利的特性,如散装插入和释放.
- 提高GIC的机械强度和抗菌疗效仍然是关键的研究目标.
- 半孔纳米粒子 (MSN) 为药物输送和材料修饰提供了一个多功能平台.
研究的目的:
- 评价树提取物加载的半孔性二氧化纳米颗粒 (EE@MSNs) 对高粘度玻璃离子体水泥 (HVGIC) 的机械性能,抗菌活性和释放的影响.
- 为了确定EE@MSN的最佳度来修改HVGIC属性.
主要方法:
- EE@MSNs进行了合成和表征.
- EE@MSNs被纳入HVGIC (富士IX) 的重量百分比为1%,3%和5%.
- 评估了压缩强度,维克斯微硬度,抗菌活性对抗突变性 estreptococcus 和释放.
主要成果:
- 与对照组相比,1%和3%的EE@MSNs的HVGIC显示了压力强度和维克尔微硬度的显著改善.
- 5%的EE@MSNs度导致机械性能下降.
- 所有经过测试的EE@MSN度都显著增加了抗菌活性和化物释放,与纳米粒子度成比例.
结论:
- 添加1%和3%的EE@MSNs是提高HVGICs机械和抗菌性能的有希望的策略.
- EE@MSNs可以改善HVGICs的化物释放.
- 进一步的研究可能会探索这些修饰的GIC的长期稳定性和临床疗效.
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