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Updated: Jan 22, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
10:49

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珀瓦纳达特诱导的氧化缓解了蛋白质氨酸激酶SRC的自身抑制

Katie E Mulholland1, Maxime Bourguet2, Nuo Cheng3

  • 1Signalling Programme, Babraham Institute, Cambridge, UK.

Science signaling
|January 20, 2026
PubMed
概括

珀瓦纳达酸通过氧化氨酸残留物激活SRC激酶,而不仅仅是抑制酸酶. 这种SRC的氧化还原调节控制其在细胞过度生长和瘤性质中的作用,需要重新评估常见的实验.

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