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Updated: Jan 22, 2026

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
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功能异质的内CD4+CD8+双阳性T细胞可以产生单阳性T细胞

Tony Li1, Arielle Ilano1, Marcel Arias-Badia1

  • 1Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, CA 94143.

Proceedings of the National Academy of Sciences of the United States of America
|January 20, 2026
PubMed
概括

双阳性 (DP) CD4+CD8+T细胞,在癌症中以前不清楚,被发现是细胞毒性,可以在瘤内分化为单阳性 (SP) T细胞. 这些DPT细胞显示出在细胞癌 (RCC) 中免疫治疗反应的生物标志物的潜力.

关键词:
在T细胞,T细胞.免疫疗法 免疫疗法瘤免疫力 免疫力

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