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Updated: Jan 22, 2026

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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多刺激激活的PROTAC前药物用于控制的蛋白质降解,增强治疗效果

Tianyang Zhou1, Yibo Gao1, Bohan Ma1

  • 1Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.

European journal of medicinal chemistry
|January 20, 2026
PubMed
概括

新的PROTAC前药被瘤微环境刺激激活,增强选择性并降低毒性. 这种方法将向蛋白质降解与自我放大光动力学疗法相结合,以获得卓越的抗瘤效果.

关键词:
这就是PROTAC.光动力学疗法是一种光动力学疗法.一个药物产品.反应性氧物种 (ROS) 是一种反应性氧物种.

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