中国成人和母亲的百日咳疫苗接种:离散选择实验的意图,偏好和定价影响
Bo Wu1, Tao Cheng2, Yanyang Zhang3
1School of Public Health, NHC Key Laboratory of Health Technology Assessment, Key Laboratory of Public Health Safety, Fudan University, Shanghai 200032, China.
Vaccine
|January 20, 2026
概括
中国的青少年,成年人和孕妇显示出高疫苗接种意图. 关键偏好包括疫苗的有效性,安全性,负担能力和国内来源,为未来的免疫战略提供信息.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 卫生经济学 卫生经济学
背景情况:
- 全球范围内,百日咳仍然是一个公共卫生问题,需要有效的免疫策略.
- 了解疫苗接种意图和偏好对于优化不同人群的疫苗接种至关重要.
研究的目的:
- 评估中国青少年,成年人和孕妇的百日咳疫苗接种意图.
- 确定关键的疫苗属性偏好,以告知中国未来的百日咳免疫战略.
主要方法:
- 在中国五个省份进行多阶段分层集群随机抽样的横截面调查.
- 离散选择实验 (DCE) 评估疫苗的疗效,不良反应,持续时间,来源和成本.
- 多变量逻辑回归和因果调解分析,以检查意图的相关性.
主要成果:
- 在所有参与者群体中观察到普遍较高的疫苗接种意向.
- 疫苗疗效是选择的主要驱动因素,其次是较低的不良事件风险,国内来源和较低的成本.
- 家庭规模和家庭主要影响了意图;百日咳的知识部分介导了教育意图的关联.
结论:
- 显著的意图和对有效性,安全性和负担能力的一致偏好,特别是对于国内生产的疫苗.
- 调查结果通过有针对性的沟通,调整定价和整合到产前服务来为计划设计提供信息.
- 需要量身定制的策略来提高中国的真实世界百日咳疫苗接种率.
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