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Updated: Jan 22, 2026

Fabrication of a Dipole-assisted Solid Phase Extraction Microchip for Trace Metal Analysis in Water Samples
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Fabrication of a Dipole-assisted Solid Phase Extraction Microchip for Trace Metal Analysis in Water Samples

Published on: August 7, 2016

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用LC-MS/MS对蛋白质消化和固体相提取策略进行比较评估,用于使用LC-MS/MS在血中的寡核酸量化

Vidya Annavarapu1, Michael G Bartlett1

  • 1Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602-2352, USA.

Journal of chromatography. A
|January 20, 2026
PubMed
概括

本研究探讨了使用固相提取 (SPE) 来提取寡核酸的新型非表面活性缓冲剂. 新方法提供了更容易的样本制备和良好的回收,用于核酸治疗药物开发.

关键词:
量化LC-MS的量化方法混合模式的SPE可以使用.橄核酸的治疗药物蛋白酶 k 预处理固相提取固相提取的方法基于表面活性剂的缓冲器微板是的微板之一.在体外稳定性

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