巨细胞HDAC10缺乏改善PM2.5诱导的肺炎,通过抑制Beclin1脱乙依赖的自

Jiewen Huang1, Jingyun Quan1, Guomei Su1

  • 1Department of Respiratory and Critical Care Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523121, China; Dongguan Key Laboratory of Immune Inflammation and Metabolism, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523121, China.

PubMed
概括

细颗粒物 (PM2.5) 暴露会通过通过HDAC10改变巨细胞自,从而引发肺炎. 抑制HDAC10可以减少炎症,为PM2.5相关的呼吸道疾病提供治疗潜力.

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