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在口腔癌患者中,吞功能,营养状况和整体生存期的术后变化之间的关系
Yu-Xuan Peng1, Yi-Chieh Tsai2, Wen-Pei Chang3
1Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan.
概括
口腔癌患者的术后吞困难与营养状况相关. 手术后改善的营养与更好的生存率有关,强调需要持续监测患者和营养支持.
科学领域:
- 在瘤学瘤学.
- 手术 手术 手术 术 术
- 营养科学 营养科学
- 吞障碍 吞障碍 吞障碍
背景情况:
- 缺食症和营养不良是口腔癌患者常见的术后并发症.
- 这些并发症增加了治疗风险,并对患者的生存率产生了负面影响.
研究的目的:
- 调查口腔癌手术后吞功能和营养状况的变化.
- 确定这些变化对患者整体存活时间的影响.
主要方法:
- 120名接受手术的口腔癌患者的回顾性队列研究.
- 收集了手术前,3个月和手术后6个月的BMI,白蛋白,功能性口服摄入量表 (FOIS) 和患者生成的主观全球评估 (PG-SGA) 的数据.
- 利用基于小组的轨迹建模和考克斯回归分析来评估时间模式和生存因素.
主要成果:
- 吞功能 (FOIS分数) 的变化与PG-SGA分数负相关,与白蛋白和BMI轨迹积极相关.
- 第四期癌症,较高的PG-SGA得分和较低的白蛋白水平与增加的死亡风险有显著的关联.
- 在120名患者中,有42名患者在平均随访时间25.36个月期间死亡.
结论:
- 口腔癌患者经历了手术后的吞受损.
- 术后吞功能与营养状况相互关联.
- 手术后的营养状况是生存的关键决定因素,强调监测和干预的重要性.
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