预后营养指数和多因子名谱用于预测预防性结节切开术后早期的口腔相关并发症:一项回顾性队列研究
Xiao Lin1, Yafei Zhang2, Yuqin Wang3
1Department of Gastrointestinal Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou City, Jiangsu Province, China; School of Medical and Health Engineering, Changzhou University, Changzhou City, Jiangsu Province, China.
概括
一种新的诺米图有效地预测了预防性结肠切除术后的早期口腔并发症,仅仅超越了预后营养指数 (PNI). 该工具有助于识别高风险患者进行有针对性的干预.
科学领域:
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
- 临床预测模型临床预测模型
背景情况:
- 在预防性结节切开术后,与静脉相关的早期并发症可能会显著影响患者的康复和结果.
- 预后营养指数 (PNI) 已经显示出评估营养状况和预测外科手术结果的潜力.
- 确定这些并发症的可靠预测因素对于优化术后管理至关重要.
研究的目的:
- 评估预后营养指数 (PNI) 和其他临床因子的预测价值,以评估在接受预防性结节切除术的患者中早期的结节相关并发症.
- 开发和验证这些并发症的预测模型.
主要方法:
- 进行了对229名接受预防性结节切除术的患者的回顾性分析.
- 接收器操作特征 (ROC) 曲线分析确定了最佳的PNI截止值.
- 单变量和多变量逻辑回归确定了独立的风险因素,导致了预测性名录的开发.
主要成果:
- 早期门相关并发症的发生率为47.2%.
- 确定了独立的风险因素,包括新辅助疗法,没有手术前静脉位标记,静脉高度<2厘米,低PNI.
- 开发的名图表显示出优异的预测性能 (AUC = 0.808),优于PNI单独模型 (AUC = 0.748).
结论:
- 开发的诺莫图谱是预测预防性结节切开术后早期结节切开术相关并发症的宝贵工具.
- 与单独的PNI相比,它表现出优越的预测性能,校准和临床实用性.
- 诺米图表促进了术后风险分层,并支持针对性的干预措施,以改善患者的治疗结果.
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