眼部疾病及其与重症监护室患者死亡率的关联:来自MIMIC-IV数据库的回顾性队列研究
Chang Gao1,2, Jing Lou3, Yuting Hu1
1Emergency and Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
BMJ open ophthalmology
|January 20, 2026
概括
患有慢性眼部疾病的重症监护室 (ICU) 患者面临更高的长期死亡率. 急性非创伤性出血性眼病与重症患者的住院死亡率增加有关.
科学领域:
- 关键护理医学 关键护理医学
- 眼科医生 眼科 眼科
- 医疗保健服务研究 医疗服务研究
背景情况:
- 眼部疾病在重症监护室 (ICU) 患者中很常见,但经常被忽视.
- 在ICU环境中,眼部疾病的并发症,临床特征和预后效应需要进行广泛的调查.
研究的目的:
- 研究重症患者眼部疾病的预后影响.
- 识别眼部疾病的ICU患者死亡的风险因素.
主要方法:
- 使用了密集护理IV数据库 (V. 2.2) 的医疗信息商城.
- 使用随机森林模型来确定与死亡率相关的因素.
- 使用多变量逻辑回归来识别急性眼病子组中医院死亡率的独立风险因素.
主要成果:
- 分析了40149名符合条件的ICU患者;9.8%患有眼部疾病.
- 患有急性眼病的患者出现急性损伤,机械通风和败血症的比率更高.
- 慢性眼病与1年死亡率显著增加有关 (log-rank p=0.0001).
- 急性非创伤性出血性眼病独立增加了住院死亡率 (OR 2.69).
结论:
- 在ICU患者的慢性眼病与长期死亡率的增加有关.
- 急性眼部疾病可能意味着在重症监护中疾病的严重程度更大.
- 急性非创伤性出血性眼病是ICU患者住院死亡率的独立预测因素.
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