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Updated: Jan 22, 2026

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系统工程的微单生虫生虫细胞工厂为甘他素C1a过度生产

Feng Xu1, Hao Gao2, Rong Ben2

  • 1State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology, East China University of Science and Technology, Shanghai 200237, China; National Center of Bio-Engineering & Technology (Shanghai), East China University of Science and Technology, Shanghai 200237, China; Shanghai Collaborative Innovation Center for Biomanufacturing Technology, East China University of Science and Technology, Shanghai 200237, China.

Trends in biotechnology
|January 20, 2026
PubMed
概括

这项研究通过优化代谢途径和生物反应器条件来设计 gentamicin C1a 的生产. 开发的框架显著提高了抗生素产量,提供了更有效的生物制造战略.

关键词:
微型单胞体 精胞体 精胞体组合代谢工程的代谢工程.发酵优化优化发酵的优化基因组规模的代谢模型.这是一种 gentamicin 药物.代谢流量分析的代谢流量分析.

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