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Updated: Jan 22, 2026

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在严重恶化的COPD中使用智能手机检测咳:一项探索性试点研究
Maximilian Boesch1,2, Julia Herrmann3, Florent Baty1
1Lung Center, HOCH Health Ostschweiz, Kantonsspital St.Gallen, Universitäres Lehr- und Forschungsspital, St.Gallen, Switzerland.
COPD
|January 20, 2026
概括
在因慢性阻塞性肺病 (AECOPD) 急性恶化住院的患者中,通过智能手机监测咳是可行的. 咳数量随着时间的推移而下降,并与临床标记相关,这表明它有可能作为早期干预的数字生物标志物.
科学领域:
- 数字健康技术数字健康技术
- 呼吸系统药物 呼吸系统药物
- 发现生物标志物的发现.
背景情况:
- 慢性阻塞性肺病 (COPD) 的发病率在全球范围内正在上升.
- 慢性肺炎的急性恶化 (AECOPD) 显著增加了发病率,死亡率和医疗保健成本.
- 通过数字健康工具远程监控患者可以改善COPD管理.
研究的目的:
- 评估在住院AECOPD患者中使用智能手机监测咳的可行性.
- 评估自动咳检测的生物标志物潜力.
- 在AECOPD恢复期间将咳计数与临床和生化标志物相关联.
主要方法:
- 一个单中心,前性,观察性队列研究招募了23名住院的AECOPD患者.
- 一个无接触的智能手机支持系统被用于自动,近乎实时的咳检测和量化.
- 咳数与临床数据和生化标志物相关.
主要成果:
- 在住院的AECOPD患者中,基于智能手机的咳检测是可行的.
- 咳的数量在入学时是最高的 (约. 15/小时) 和在恢复期间下降 (到<5/小时).
- 咳数量显示日间变化,与氧气和相反相关,与体温有正相关.
结论:
- 使用智能手机自动监测咳对于AECOPD患者来说是一个可行的工具.
- 咳数量反映了疾病状态,与关键临床指标相关.
- 这项技术可以实现远程监控,并作为AECOPD的早期数字生物标志物,促进及时干预和节省成本.
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