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在CRSsNP中症状负担的系统预测因素:三种患者报告的结果措施的横截面比较

María Alharilla Montilla-Ibáñez^1,2, Javier Modesto García-Fernández^3,4, María Pilar Gómez-Gallego^1,2

¹Department of Health Sciences, University of Jaén, Jaén, Spain.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|January 20, 2026

概括

诸如年龄和吸烟等社会人口统计学因素影响了无鼻息肉慢性鼻炎 (CRSsNP) 的症状负担. 患者报告的结果指标 (PROM) 对这些因素的敏感性各不相同,睡眠呼吸暂停的相关性可能是由问卷内容驱动的.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
健康结果研究研究结果

背景情况:

没有鼻息肉的慢性鼻炎 (CRSsNP) 显著影响患者的生活质量.
了解影响症状负担的因素对于有效管理至关重要.
患者报告的结果测量 (PROM) 是评估CRSsNP症状的重要工具.

研究的目的:

调查社会人口统计学和临床变量如何影响CRSsNP中的症状负担.
为了比较三个PROM (NOSE-E,SNOT-22,CRS-PRO) 对这些预测者的灵敏度.
评估睡眠相关项目对阻塞性睡眠呼吸暂停 (OSA) 和PROMs之间的关联的影响.

主要方法:

一项涉及50名在第三级护理医院中患有CRSsNP的成年人的横截面研究.
收集了社会人口统计学 (年龄,性别,BMI,吸烟) 和临床变量 (过敏性鼻炎,喘,OSA,先前的鼻腔手术) 的数据.
单变量和多变量线性回归分析了NOSE-E,SNOT-22和CRS-PRO的预测因素;进行了无睡眠分析.

主要成果:

每个PROM都表现出独特的预测者配置文件.
年龄和吸烟预测了NOSE-E得分;之前的鼻腔手术预测了SNOT-22得分.
阻塞性睡眠呼吸暂停 (OSA) 与CRS-PRO的关联是由与睡眠有关的项目介导的,在无睡眠分析中消失了.

结论:

社会人口统计学和生活方式因素对CRSsNP症状报告具有仪器特异性影响.
OSA和CRS-PRO之间的关联受睡眠相关内容的影响,而不仅仅是鼻症状.
对PROM的域意识解释是必不可少的,特别是在睡眠并发症患者中.

关键词:

这就是CRS-PRO.这就是CRSsNP.慢性鼻炎是什么意思慢性鼻炎鼻子 - 眼睛这些是PROMs.生活质量生活的质量.这就是SNOT-22的意思.睡眠呼吸暂停 (Sleep Apnea) 是一种疾病.症状预测因素症状预测因素

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