不故意使用二胺和使用药物检查服务的频率:一个横截面研究
Lauren Airth1,2,3, Trevor Goodyear1,4, Brandon D L Marshall5
1British Columbia Centre On Substance Use, 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada.
Harm reduction journal
|January 20, 2026
概括
二二胺的造正在上升. 频繁的不受监管的阿片类药物使用,而不是无意的二二类药物消费,预测了药物检查服务 (DCS) 的使用. 在加拿大药物检查服务中,性别没有改变这种关系.
科学领域:
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
- 药品检查服务 药品检查服务
背景情况:
- 在不受监管的药物供应中,二胺改剂的流行率越来越高.
- 药物检查服务 (DCS) 对于识别未知物质至关重要.
- 了解影响DCS利用的因素对于降低危害至关重要.
研究的目的:
- 为了检查疑似非故意的二二类药物消费和DCS使用频率之间的联系.
- 调查性别是否改变了二胺暴露和DCS使用之间的关系.
- 为了确定频繁的药物检查服务参与的关键预测因素.
主要方法:
- 在加拿大不列颠哥伦比亚省进行的横截面研究 (2021-2023年).
- 使用光谱和免疫测试条进行药物分析.
- 多变量顺序逻辑回归分析了DCS利用频率,控制了阿片类药物使用和年龄等混因素.
主要成果:
- 超过65%的参与者认为他们无意中服用了二.
- 初步分析显示,非故意使用二和DCS频率之间存在联系.
- 在调整频繁的未经监管的阿片类药物使用后,这种关联变得无意义;性别没有改变这种关系.
结论:
- 频繁的不受管制的阿片类药物使用似乎是DCS利用的主要驱动因素.
- 虽然性别没有显著改变这种关联,但对其作用的进一步研究是有必要的.
- 调查结果突出了物质使用模式和减少伤害服务参与的复杂相互作用.
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