皮克林粒子随机顺序吸附到球形乳液滴滴表面上
Yi Feng1, Giulia Del Duca1, Antonio Buffo1
1Politecnico di Torino, Department of Applied Science and Technology, Torino, Italy.
Physical review. E
|January 21, 2026
概括
对于食品和制药来说至关重要的皮克林乳液,使用新的随机顺序吸附 (RSA) 模型可以更好地理解. 这种模型准确地预测了乳液滴上的粒子吸附,即使是复杂的粒子形状.
科学领域:
- 合体和表面科学科学
- 材料科学 材料科学 材料科学
- 计算化学计算化学
背景情况:
- 皮克林乳液越来越多地用于制药和食品中,因为它们的稳定性和低毒性.
- 在乳液接口的颗粒吸附是乳液性质的关键,但对于非球形颗粒来说是复杂的.
- 现有的模型往往简化了粒子形状和表面相互作用,限制了预测准确度.
研究的目的:
- 开发和验证一种用于粒子随机顺序吸附 (RSA) 到乳液滴表面的新模型.
- 为了研究粒子形状 (球形与延长形状),大小和界面特性对吸附的影响.
- 提出改进的可用表面功能 (ASF) 和通用覆盖范围演变模型.
主要方法:
- 蒙特卡洛 (MC) 模拟被用来为球形和延长粒子建模RSA过程.
- 研究的参数包括粒子多分散性,滴与粒子大小比,接触角度和粒子度.
- 使用响应表面方法来建立基于模拟数据的通用覆盖演变模型.
主要成果:
- 为可用表面函数 (ASF) 提出了一种新的覆盖范围依赖指数,其性能优于固定指数模型.
- 对于囊形颗粒 (面积比 ε=2),观察到更高的覆盖率和更快的吸附率.
- 一般化的模型显示出高准确度,平均绝对百分比误差低于球形粒子的2.63%,长长粒子的6.58%.
结论:
- 开发的RSA模型和拟议的ASF表达精确地预测了粒子吸附在曲面乳液滴面上的粒子吸附,考虑到粒子形状.
- 这些发现为设计具有特定功能的稳定皮克林乳液提供了更强大的理论框架.
- 这项工作增强了对各种工业应用相关的复杂体系统的接口现象的理解.
相关概念视频
01:23Spherical Coordinates
14.9K
Spherical coordinate systems are preferred over Cartesian, polar, or cylindrical coordinates for systems with spherical symmetry. For example, to describe the surface of a sphere, Cartesian coordinates require all three coordinates. On the other hand, the spherical coordinate system requires only one parameter: the sphere's radius. As a result, the complicated mathematical calculations become simple. Spherical coordinates are used in science and engineering applications like electric and...
14.9K
01:23Factors Affecting Dissolution: Particle Size and Effective Surface Area
1.6K
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
1.6K
01:09Analyte Adsorption and Distribution
2.5K
In certain chromatographic separations, solutes transfer between the mobile phase and the stationary phase via sorption, which typically refers to the process of adsorption. For many chromatographic systems, the sorption process often depends on the polarity of the compounds—an expression of the overall dipole moment within the molecule. During the separation process, there is competition between the solute and solvent for adsorption to the stationary phase. Highly polar compounds and...
2.5K
01:26Spherical and Cylindrical Capacitor
6.7K
A spherical capacitor consists of two concentric conducting spherical shells of radii R1 (inner shell) and R2 (outer shell). The shells have equal and opposite charges of +Q and −Q, respectively. For an isolated conducting spherical capacitor, the radius of the outer shell can be considered to be infinite.
Conventionally, considering the symmetry, the electric field between the concentric shells of a spherical capacitor is directed radially outward. The magnitude of the field,...
Conventionally, considering the symmetry, the electric field between the concentric shells of a spherical capacitor is directed radially outward. The magnitude of the field,...
6.7K
01:27Gravity between Spherical Bodies
9.3K
Newton's law of gravitation describes the gravitational force between any two point masses. However, for extended spherical objects like the Earth, the Moon, and other planets, the law holds with an assumption that masses of spherical objects are concentrated at their respective centers.
This assumption can be proved easily by showing that the expression for gravitational potential energy between a hollow sphere of mass (M) and a point mass (m) is the same as it would be for a pair of extended...
This assumption can be proved easily by showing that the expression for gravitational potential energy between a hollow sphere of mass (M) and a point mass (m) is the same as it would be for a pair of extended...
9.3K
01:04Random Error
9.1K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
9.1K