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Thermodynamics: Chemical Potential and Activity01:10

Thermodynamics: Chemical Potential and Activity

1.7K
The effective concentration of a species in a solution can be expressed precisely in terms of its activity. Activity considers the effect of electrolytes present in the vicinity of the species of interest and depends on the ionic strength of the solution. The activity of a species is expressed as the product of molar concentration and the activity coefficient of the species.
The thermodynamic equilibrium constant is more accurately defined in terms of activity rather than concentration.
1.7K
Chemical Formulas02:52

Chemical Formulas

60.9K
A chemical formula presents information about the proportions of atoms constituting a particular chemical compound or molecule, mainly using symbols of elements and numbers. At times other symbols, such as dashes, parentheses, brackets, commas, plus, and minus signs, are also used. A chemical formula can be one of three types – molecular, empirical, and structural.
60.9K
Chemical Equations03:10

Chemical Equations

80.7K
Chemical equations represent the identities and relative quantities of substances involved in a chemical reaction. The substances undergoing reaction are called reactants, and their formulas are placed on the left side of the equation. The substances generated by the reaction are called products, and their formulas are placed on the right side of the equation. Plus signs (+) separate individual reactant and product formulas, and an arrow (→) separates the reactant and product (left and right)...
80.7K
Chemical Reactions01:19

Chemical Reactions

95.3K
A chemical reaction is a process by which the bonds in the atoms of substances are rearranged to generate new substances. Matter cannot be created or destroyed in a chemical reaction—the same type and number of atoms that make up the reactants are still present in the products. Merely, the rearrangement of chemical bonds produces new compounds.
Chemical Reactions Rearrange Atoms into New Substances
A chemical reaction takes starting materials—the reactants—and changes them...
95.3K
Activation Energy01:26

Activation Energy

86.4K
Activation energy is the minimum amount of energy necessary for a chemical reaction to move forward. The higher the activation energy, the slower the rate of the reaction. However, adding heat to the reaction will increase the rate, since it causes molecules to move faster and increase the likelihood that molecules will collide. The collision and breaking of bonds represents the uphill phase of a reaction and generates the transition state. The transition state is an unstable high-energy state...
86.4K
Gene-Environment Interactions01:20

Gene-Environment Interactions

1.1K
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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相关实验视频

Updated: Jan 22, 2026

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
08:20

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

Published on: May 1, 2020

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在拥挤的环境中,化学活性滴滴.

Jacques D Fries1, Roxanne Berthin1, Chengjie Luo2

  • 1PHENIX, CNRS, Sorbonne Université, Physico-Chimie des Électrolytes et Nanosystèmes Interfaciaux (, ), 4 Place Jussieu, 75005 Paris, France.

Physical review. E
|January 21, 2026
PubMed
概括
此摘要是机器生成的。

大分子拥挤令人惊地缩小了化学活性滴,但扩大了它们的密集相位体积. 这是由于这些不平衡系统中的相互作用和粒子流动造成的.

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Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes
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Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes

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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding

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相关实验视频

Last Updated: Jan 22, 2026

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
08:20

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

Published on: May 1, 2020

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Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes
10:43

Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes

Published on: July 19, 2022

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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
09:14

Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding

Published on: August 22, 2016

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科学领域:

  • 细胞生物学 细胞生物学
  • 生物物理学的生物物理.
  • 软物质物理学 软物质物理学

背景情况:

  • 生物分子凝聚物通过相位分离来组织细胞.
  • 化学活跃的液滴在动态状态下使用非平衡反应.
  • 目前的模型缺乏分子细节,特别是在拥挤的细胞环境中.

研究的目的:

  • 调查宏分子拥挤如何影响化学活性滴.
  • 探索分子级效应和这些凝结物中的运输.
  • 了解活跃滴和之间的相互作用.

主要方法:

  • 利用基于粒子的模拟来获得分子洞察力.
  • 采用基于现场的模拟来补充粒子模型.
  • 分析了拥挤,耗尽相互作用和粒子流动的综合效应.

主要成果:

  • 拥挤出乎意料地减少了滴滴大小.
  • 滴滴的整体密度增加了.
  • 观测到枯竭,扩散阻碍和不平衡流动之间的相互作用.

结论:

  • 拥挤显著改变了化学活性滴滴的行为.
  • 这些发现挑战了对活跃滴滴的基于平衡的预测.
  • 在现实的细胞条件下提供对活跃滴滴动态的见解.