在养老院治疗呼吸道感染的抗生素使用:一项多中心的横截面研究
Carl Llor1,2,3, Rosa Morros1,2,4, Jesús Mateos-Nozal5
1Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol, Barcelona, Spain.
Frontiers in pharmacology
|January 21, 2026
概括
在西班牙养老院,过度使用抗生素治疗呼吸道感染 (RTIs) 的比例很高,63.1%的处方是不必要的. 需要采取干预措施,以改善基于指南的处方,并减少不适当的抗生素使用.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 呼吸道感染 (RTIs) 在养老院居民中很常见.
- 在这一群体中,用于RTIs的抗生素使用需要仔细评估,以防止耐药性和不良影响.
研究的目的:
- 评估西班牙养老院RTIs的抗生素治疗模式.
- 根据当前的指导方针来确定抗生素处方的适当性.
- 识别与抗生素使用和滥用相关的因素.
主要方法:
- 在西班牙34个养老院进行了横截面研究.
- 护理人员记录了有关RTIs患者及其抗生素使用情况的数据.
- 后勤回归模型确定了抗生素处方和不适当使用的预测因素.
主要成果:
- 在533例RTI病例中,77.5%的抗生素被处方.
- 63.1%的评估抗生素处方被认为是不必要的.
- 混乱,感知需求和发烧预测了抗生素的使用,而鼻减少了.
结论:
- 在养老院观察到大量过度使用抗生素治疗RTIs.
- 有针对性的干预措施是必要的,以促进符合指导方针的处方,并减少不适当的抗生素使用.
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