探索暴露与精子质量之间的关联:系统性审查和元分析
Rohit Gautam1, Eepsita Priyadarshini2, Pratibha Maan1
1Division of Reproductive Child Health and Nutrition, Indian Council of Medical Research, New Delhi, India.
Journal of human reproductive sciences
|January 21, 2026
概括
暴露可能会减少精液量,但其对精子度和运动性的影响尚不清楚. 需要更多的研究来证实这些关于男性生殖健康的发现.
科学领域:
- 环境健康 环境健康
- 生殖毒理学 生殖毒理学
- 人类健康风险评估
背景情况:
- 是一种广泛存在于食物,水和空气中的环境毒素.
- 暴露于,无论是急性还是慢性,都会给健康带来重大风险.
- 研究表明对男性生殖系统有负面影响.
研究的目的:
- 系统地审查和评估暴露对人类精液质量影响.
- 确定暴露水平与精液质量参数下降之间的关联.
主要方法:
- 在Scopus,PubMed和Cochrane中央数据库中进行了系统的文献搜索.
- 在独立审查员进行两步选过程后,包括了四项研究.
- 两项横截面研究被汇总为元分析;两项病例控制研究被描述为叙述.
主要成果:
- 分析表明,综合平均精液量,精子度和精子运动率在WHO参考值或以上,尽管异质性很高.
- 对的暴露与对精液体积的潜在负面影响有关.
- 在包括的研究中,对精子度和运动性的影响是不一致的.
结论:
- 暴露可能会对精液量产生负面影响,但对精子度和运动性的影响的证据是不确定的.
- 有限的研究和方法的变化限制了关于的生殖毒性的最终结论.
- 需要大规模的纵向研究和标准化的评估来验证这些发现并确定因果关系.
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