改变PCOS女性的形象:一个15年的回顾性队列研究
1Department of Obstetrics and gynaecology, Kar Clinic and Hospital Pvt Ltd., Bhubaneswar, Odisha, India.
Journal of human reproductive sciences
|January 21, 2026
概括
患有多囊卵巢综合征 (PCOS) 的印度女性的代谢和临床概况在15年内显著恶化,肥胖和代谢综合征增加. 这凸显了早期生活方式干预和公共卫生战略的迫切需要.
科学领域:
- 内分泌学 在内分泌学.
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 多囊卵巢综合征 (PCOS) 影响全球5-10%的生殖年龄女性.
- 由于生活方式的改变,印度面临着越来越多的肥胖和代谢问题.
- 这项研究追踪了印度奥迪沙州15年来PCOS的进展情况.
研究的目的:
- 分析PCOS妇女临床,表型,生化和代谢参数的时间变化.
- 评估过去二十年来印度PCOS患者不断变化的健康状况.
主要方法:
- 对1530名被诊断患有PCOS的女性进行了回顾性图表审查 (罗德堡标准).
- 数据分为三个五年期 (2009-2024年) 的数据.
- 使用统计测试 (千平方,克鲁斯卡尔-瓦利斯) 在不同时期进行人体测量,生化和超声波特征的比较.
主要成果:
- 观察到平均BMI (26.4至28.4公斤/米2),腰围 (86.8至90.8厘米) 和异常葡萄糖耐受性的显著增加.
- 越来越多的PCOS,糖尿病,高血压,肥胖和脂质不良的家族病史.
- 代谢综合征的患病率从36.5%增加到45.6%.
结论:
- 在过去的15年里,印度女性患有PCOS的代谢和表型特征显著恶化.
- 对于早期的生活方式干预非常需要.
- 公共卫生战略必须针对PCOS人口中的代谢风险因素.
相关概念视频
Other Nuclides: 31P, 19F, 15N NMR
756
Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
756
Global Climate Change
28.7K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.7K
Work Done During Volume Change
5.1K
In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process.
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
5.1K
Net Change Theorem
59
The Net Change Theorem is a fundamental principle in calculus that establishes a direct relationship between a function’s rate of change and its accumulated change over an interval. Mathematically, it states that the definite integral of a function's derivative over a given interval [a,b] yields the net change in the original function:This theorem has significant applications in various real-world scenarios, including physics, economics, and engineering. A particularly useful application...
59
Standard Entropy Change for a Reaction
24.0K
Entropy is a state function, so the standard entropy change for a chemical reaction (ΔS°rxn) can be calculated from the difference in standard entropy between the products and the reactants.
24.0K
Le Chatelier's Principle: Changing Temperature
35.1K
Consistent with the law of mass action, an equilibrium stressed by a change in concentration will shift to re-establish equilibrium without any change in the value of the equilibrium constant, K. When an equilibrium shifts in response to a temperature change, however, it is re-established with a different relative composition that exhibits a different value for the equilibrium constant.
To understand this phenomenon, consider the elementary reaction:
To understand this phenomenon, consider the elementary reaction:
35.1K


