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Updated: Jan 22, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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Published on: August 20, 2019

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身份,而不是3D位置,在人类基因组中告知了罕见内核的拼接

Saren M Springer1,2, Katherine Fleck3,2, Kaitlin N Girardini1

  • 1Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA.

iScience
|January 21, 2026
PubMed
概括

这项研究绘制了核中的内部组织图,发现内部类型,而不是位置,决定了拼接效率. 小型内子表现出独特的核排列,特别是在癌细胞中,影响它们的拼接.

关键词:
细胞生物学 细胞生物学分子结构 分子结构分子生物学分子生物学

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