高海拔对深静脉血栓形成的影响:一个多中心队列研究
Kaysie L Banton1, Stephanie Jarvis2, Cyprien Gabriel Jungels3
1Trauma Services Department, Swedish Medical Center, Seattle, Washington, USA.
Trauma surgery & acute care open
|January 21, 2026
概括
高空受伤显著增加了深静脉血栓塞 (DVT) 的风险. 处于较高海拔地区的创伤中心可能需要加强DVT查和预防方案,以获得更好的患者结果.
科学领域:
- 医学研究 医学研究
- 创伤外科 手术 创伤外科
- 血管医学 血管医学
背景情况:
- 之前关于升高和深静脉血栓形成 (DVT) 的研究具有有限的升高范围,并专注于特定的创伤子集.
- 这项研究提供了一个全面的分析,在所有创伤入院中,不同高度和DVT之间的关联.
研究的目的:
- 研究创伤患者的损伤升高和深静脉血栓形成 (DVT) 发生率之间的关系.
- 为了确定更高的升高是否与DVT的风险增加有关.
主要方法:
- 一项回顾性队列研究,涉及四个I级创伤中心的成年创伤患者.
- 受伤的高度根据邮政编码确定,并分为高海拔 (≥5000英尺) 和低海拔 (<5000英尺) 组.
- 统计学意义被设定为<0.0001.1的α.
主要成果:
- 高海拔受伤 (≥5000英尺) 与低海拔受伤 (0.5%) 相比,与DVT (1.9%) 的发生率显著增加有关.
- 每增加1000英尺的海拔高度与DVT率平均增加0.4%相关.
- 在对共变量进行调整后,高空受伤显示DVT的风险增加了3.8倍.
结论:
- 高空受伤独立地与发展DVT的显著更高风险有关.
- 伤害升高和DVT率之间存在正线性关联.
- 在高海拔创伤中心,可能需要加强DVT查和预防.
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