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Updated: Jan 22, 2026

Genetic Screen for Identification of Multicopy Suppressors in Schizosaccharomyces pombe
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互动组查表明BAG6是ALS/FTD中UBQLN2错折的抑制剂

Sang Hwa Kim1, Claire E Boos2, Mark Scalf2

  • 1Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

Frontiers in molecular neuroscience
|January 21, 2026
PubMed
概括

与ALS/FTD相关的乌比基林-2 (UBQLN2) 突变破坏了蛋白质的功能. 这项研究将BAG6确定为UBQLN2保持酶,并揭示了改变的蛋白相互作用,有助于神经退行性疾病病理学.

关键词:
这就是ALS.BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6 BAG6这是一个FTD.在PEG10的基础上,PEG10UBQLN2 的时间.

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