在资源有限的环境中优化多发性骨髓瘤治疗:当前的观点和挑战
Bishal Tiwari1,2, Samita Sapkota3
1Nassau University Medical Center, East Meadow, Long Island, NY 11554, USA.
Ecancermedicalscience
|January 21, 2026
概括
多发性骨髓瘤 (MM) 管理面临着全球性的挑战,尤其是在资源有限的环境中. 改善对诊断的获取和适应治疗对于更好的结果和减少健康不平等至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 全球健康 全球健康
背景情况:
- 多发性骨髓瘤 (MM) 的发病率和死亡率在全球范围内不断上升.
- 高收入国家和低收入和中等收入国家 (LMICs) 之间在MM诊断和治疗方面存在显著差异.
研究的目的:
- 批判性地审查当前的MM管理策略.
- 突出资源有限的环境中的差异.
- 提出改善全球MM护理的策略.
主要方法:
- 在多个数据库中进行全面的文献搜索 (2010-2024年).
- 分析同行评审的文章,临床指南和会议摘要.
- 在不同收入环境中对治疗方法的比较分析.
主要成果:
- 高收入国家利用先进的治疗方案,干细胞移植和新的维持疗法.
- 低低收入国家往往依赖于不那么有效,更实惠的治疗方法,因为他们对先进的诊断和高成本的治疗方法的获取有限.
- 关键的挑战包括迟到提交,基础设施不足,经济限制和劳动力短缺.
结论:
- 提高诊断能力至关重要.
- 需要调整资源分层处理指南.
- 通过政策和协作加强医疗保健系统,可以弥合护理差距,减少MM管理中的全球不平等.
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