在COVID-19幸存者中肌肉骨症状和COVID后功能状态:单中心前性观察研究
Laxman Choudhary1, Nitesh Gahlot2, Sanjeev Misra3
1Department of Trauma and Emergency (Orthopaedics), All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
概括
许多COVID-19幸存者经历了持续的肌肉骨 (MSK) 症状,如疲劳和关节疼痛,特别是那些初始症状和并发症的人. 在这些患者中,功能限制更为常见,这凸显了对长期MSK影响的进一步研究的需要.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
背景情况:
- 在COVID-19后的诊所中观察到肌肉骨 (MSK) 症状的发病率增加.
- 需要了解COVID-19康复后一年的MSK症状的流行程度和影响.
- 确定与MSK症状严重程度和发病率相关的因素至关重要.
研究的目的:
- 为了确定COVID-19患者康复1年后MSK症状的频率.
- 评估这些患者的功能状态.
- 确定发展和加剧MSK症状的危险因素.
主要方法:
- 一个单一中心的前性观察研究.
- 从2020年3月到12月,涉及到1954名住院COVID-19患者.
- 在获得知情同意后,通过电话问卷收集的数据.
主要成果:
- 在1954名患者中,有1087人报告MSK症状,最常见的是疲劳 (50.71%),肌痛,背痛和关节疼痛.
- 患有COVID-19症状的患者患关节疼痛的风险增加了3.37倍.
- 患有≥2种并发症的人患关节疼痛的风险高出2.27倍.
- 功能限制在MSK组 (88.78%) 与非MSK组 (55.02%) 相比显著更高.
结论:
- 疲劳是COVID-19后最常见的MSK症状.
- 症状性COVID-19和多种并发症增加了长期关节疼痛的风险.
- 虽然大多数患者在一个月内恢复身体状态,但MSK问题需要进一步调查长期影响.
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