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Updated: Jan 22, 2026

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来自HUNT4Echo研究的肌动脉工作指数的心声学参考范围
Ingrid Yttervoll1, Andreas Østvik1,2,3, John Nyberg1
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Mailbox 8905, Trondheim 7491, Norway.
European heart journal. Imaging methods and practice
|January 21, 2026
概括
现在已经为健康人群建立了心肌工作指数的参考范围. 虽然年龄和性别表现出较小的影响,但压力-应变循环形状的变化凸显了需要整合应变和后负荷来准确评估左心室功能.
科学领域:
- 心脏病学 心脏病学
- 心血管生理学心血管生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 心肌工作指数,包括全球工作指数 (GWI),全球建设性工作 (GCW),全球浪费工作 (GWW) 和全球工作效率 (GWE),对于评估负载调整的左心室功能至关重要.
- 确定这些指数的参考范围至关重要,特别是在数据稀缺的老年人群中.
研究的目的:
- 确定心肌工作指数和压力-应变循环特征在健康,广泛的年龄范围的人群中的参考值.
- 研究年龄和性别对这些心血管参数的影响.
主要方法:
- 利用了来自HUNT4Echo研究的指导指南指导的心声回声记录.
- 通过2D斑点跟踪评估全球纵向应变,通过手臂测量测量系统血压.
- 在1239名健康参与者 (平均年龄57岁) 中,确定门事件时间以进行准确的心肌工作计算.
主要成果:
- 已建立的参考范围:GWI (1367-2583 mmHg%),GCW (1664-2972 mmHg%),GWW (38-328 mmHg%) 和GWE (88-98%). 这两种标准均为标准.
- 确定了与年龄相关的GWI和GWE的下降,以及GCW和GWW的增加 (P <0.05).
- 观察到基于性别的差异,女性呈现较高的GWI和GCW (P ≤0.001). 压力-应变环形状随着年龄的增长而缩小,尽管GWI是恒定的.
结论:
- 心肌工作指数受年龄和性别的影响,尽管这些影响在临床上意义有限.
- 尽管保持了GWI,但随着年龄的增长,压力-应变环形状的变化强调了在左心室功能评估中考虑应变和后负荷的重要性.
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