计算机辅助认知行为治疗对接受功能性内镜外科手术的患者焦虑的影响:前额外血动力学功能的探索性fNIRS研究
Yang Yang1, Haibin Zhang2, Chen Hu3
1Department of Emergency, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Frontiers in psychiatry
|January 21, 2026
概括
计算机辅助认知行为疗法 (cCBT) 改善了前额叶皮层 (PFC) 的激活,并减少了接受功能性内镜外科手术 (FESS) 的患者的焦虑. 这种非药物治疗方法有效地缓解了焦虑和失眠症状.
科学领域:
- 神经外科 神经外科
- 精神病学是一个精神病学.
- 医疗成像医学成像
背景情况:
- 在接受功能性内镜外科手术 (FESS) 的患者中,焦虑很常见.
- 在焦虑患者中,前额叶皮层 (PFC) 的激活可能发生变化.
- 功能近红外光谱 (fNIRS) 可以通过非侵入性方式评估大脑活动.
研究的目的:
- 在焦虑FESS患者中研究PFC激活.
- 评估计算机辅助认知行为疗法 (cCBT) 在调节PFC活动和临床症状方面的有效性.
主要方法:
- 60名FESS患者被随机分配到cCBT或主动对照 (健康教育) 组.
- fNIRS在口头流利任务 (VFT) 中测量了前额头血动力学反应.
- 焦虑,抑郁和失眠都被评估在外科手术期间.
主要成果:
- 与对照组相比,cCBT组显示PFC激活显著增加 (更多的道,更高的氧-Hb变化).
- 特定的PFC通道活性与减少焦虑和失眠相关.
- cCBT干预改善了临床症状,并增强了PFC的血液动力功能.
结论:
- 在FESS患者中,焦虑与减少PFC激活有关.
- cCBT是一种有效的非药物干预,用于管理FESS患者的焦虑和失眠.
- fNIRS可以监测治疗诱导的大脑功能的变化.
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