适应性过度激活可以在情绪障碍问卷上获得积极的分数吗? 来自社区调查中的病例控制研究的证据
Michela Atzeni1, Michele Fornaro2, Massimo Tusconi3
1Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Frontiers in psychiatry
|January 21, 2026
概括
情绪障碍问卷 (MDQ) 识别了过度活跃的个体,但显著的子组显示出高生活质量和最小的精神问题,表明适应性功能而不是疾病.
科学领域:
- 精神病学是一个精神病学.
- 心理评估 心理评估
- 心理健康研究 心理健康研究
背景情况:
- 双极性障碍 (BD) 的诊断是具有挑战性的.
- 情绪障碍问卷 (MDQ) 可以识别多种多样的过度激活模式,包括非病理的模式.
研究的目的:
- 调查MDQ阳性个体是否包括具有适应性过活化,高生活质量 (QoL) 和最小精神病发病率的子组.
- 确定MDQ的阳性是否也表明了除双极性障碍之外的诊断.
主要方法:
- 一项病例控制研究分析了来自意大利大型社区调查的数据.
- 参与者包括DSM-IV临床访谈和MDQ查.
- 具有MDQ阳性的个体按QoL分层 (SF-12分数>40对≤40),与匹配的MDQ阴性对照进行了分层.
主要成果:
- 33%的MDQ阳性个体 (总共91) 具有高的QoL和较少的精神病诊断,与低QoL的MDQ阳性个体相比 (χ2=15.529,p<0.0001).
- 高质量的MDQ阳性个体表现出类似于MDQ阴性对照的精神病发病率.
- 低质量的MDQ阳性个体有更高的焦虑率,强迫症和饮食障碍.
结论:
- MDQ阳性表明一个异质的群体,包括具有适应性过活化和保存功能的人.
- 需要精细的仪器来区分自适应性和病理性过度活化.
- 临床医生和公共卫生专业人员应避免过度病理化MDQ的阳性.
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