使用降低了严重COVID-19的风险:与氨酸使用者和其他COVID-19患者进行大规模比较
Chen Avni1,2, Uri Blasbalg1, Paz Toren1,2
1Ramat-Chen Brüll Mental Health Center, Tel-Aviv District, Clalit Health Services Community Division, Tel Aviv, Israel.
Frontiers in psychiatry
|January 21, 2026
概括
在一项大型人口研究中,的使用与严重的COVID-19结果的风险显著降低有关. 然而,酸与风险增加有关,这表明的潜在保护作用.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 是一种情绪稳定剂,具有免疫调节和抗病毒特性.
- 以前的假设表明,可以减轻COVID-19的严重程度,但人口层面的数据有限.
研究的目的:
- 调查使用或氨酸和严重的COVID-19结果之间的关联.
- 在一个大群体中评估对严重的COVID-19的保护潜力.
主要方法:
- 在以色列对超过149万名确诊COVID-19的成年人进行了回顾性队列研究.
- 基于持续的,烯酸盐或没有药物暴露的分类.
- 严重的COVID-19定义为住院,呼吸支,ECMO或死亡;使用反向概率权重和后勤回归分析.
主要成果:
- 使用与严重COVID-19的几率明显降低有关,尽管使用者年龄较大,并患有更多的并发病.
- 瓦尔酸盐的使用与严重COVID-19结局的风险增加有关.
结论:
- 可能会对严重的COVID-19产生保护作用,无论患者的脆弱性如何.
- 这些发现支持进一步研究心理药物的更广泛的健康影响,包括它们在传染病结果中的作用.
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