手术部位感染的发生和相关的风险因素:一个匹配的病例控制研究
Nassab Fakhreddine1,2, Hani Dimassi1, Wissam Kabbara1
1Lebanese American University School of Pharmacy, Byblos, Lebanon.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|January 21, 2026
概括
老年患者和低白蛋白水平的患者面临更高的手术部位感染 (SSI) 风险. 在长时间的手术中重新服用抗生素可能会减少SSI的发生,这是对感染控制的关键发现.
科学领域:
- 传染性疾病 传染性疾病
- 外科手术的结果
- 医疗流行病学 医疗流行病学
背景情况:
- 手术部位感染 (SSIs) 是患者发病率,死亡率和医疗保健成本增加的主要原因.
- 识别风险因素和致病微生物对于有效的预防策略至关重要.
研究的目的:
- 确定与手术部位感染 (SSI) 相关的风险因素.
- 确定涉及SSI的微生物类型.
- 分析手术患者的抗生素敏感性模式.
主要方法:
- 进行了一项追溯匹配病例对照研究.
- 分析了五年来手术患者的数据.
- 根据性别和手术类型,113例SSI病例与243例对照病例 (1:3比) 相匹配.
主要成果:
- 低albuminemia (白蛋白<3.5g/dL) 和65岁以上的年龄与增加的SSI风险显著相关 (P = .025和P = .039).
- 在手术期间重新服用抗生素显示出保护作用,降低了SSI几率 (OR = 0.19,P = .042).
- 胃肠道手术的SSI率最高 (42.3%).
结论:
- 老年患者和那些患有低albuminemia的人有SSI的风险更高.
- 在长时间的手术中重新服用抗生素可能会降低SSI的风险.
- 引起SSI的常见微生物包括大肠杆菌和凝结酶阴性葡萄球菌.
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