G-计算量化虫减少世界卫生组织儿童糖限量
A T M Dao1,2,3, L G Do1, N Stormon1,4
1School of Dentistry, Faculty of Health and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Journal of dental research
|January 21, 2026
概括
减少自由糖摄入量 (FSI) 显著降低了早期儿童 (ECC). 将FSI降低到世卫组织的目标,可以防止84-97%的学前儿童的腐烂,缺失和填充表面 (dmfs).
科学领域:
- 公共卫生 公共卫生
- 儿科牙科 儿科牙科
- 营养科学 营养科学
背景情况:
- 非传染性疾病,包括牙损伤,与高自由糖摄入量 (FSI) 有关.
- 世界卫生组织 (WHO) 建议FSI低于估计能源需求 (EER) 的10%,理想情况下低于5%,以防止这些情况.
- 尽管有建议,但在减少FSI以预防幼儿 (ECC) 的进展是微不足道的.
研究的目的:
- 量化将FSI降低至世卫组织推的值对幼儿腐烂,缺失和填充表面 (dmfs) 评分的影响.
- 确定与童年早期dmfs相关的FSI的经验值.
主要方法:
- 分析了SMILE出生队列中的2,182名澳大利亚儿童的数据.
- 使用G计算分析来估计在减少的FSI场景下 (低于10%和5%的EER) 的反事实dmfs得分.
- 通过使用受限立方线进行剂量反应分析,以模拟dmfs作为连续FSI的函数.
主要成果:
- 据估计,将FSI降低到<10%或<5%的EER将dmfs分别减少1.3和1.5,在一般学龄前人口中 (84%和97%的归因分数).
- 在高危儿童中,dmfs的减少更为显著,绝对减少为4.4-4.5%,可归因分数为75-99%.
- 增加dmfs的经验值被确定为大约6.25g/day (2.5%EER),低于世卫组织指南.
结论:
- 将FSI降低至10%以下的EER对于所有儿童至关重要,高风险群体建议目标为5%以下.
- 结果提供了证据,支持临床指导和公共卫生干预措施,旨在降低幼儿期的FSI.
- 需要在不同的环境中进行进一步的研究,包括低收入和中等收入国家,以告知全球降糖政策.
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