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Updated: Jan 22, 2026

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跨祖先多基因预测:比较方法和评估跨特征的可转移性.

Md Moksedul Momin1,2,3,4, Xuan Zhou1,2,4, Muktar Ahmed1,4,5

  • 1Australian Centre for Precision Health, University of South Australia, Adelaide, Australia.

Genetic epidemiology
|January 21, 2026
PubMed
概括

多基因风险评分 (PGS) 方法在预测复杂特征时,在祖先之间表现不同. 像GBLUP和PRS-CSx这样的特定方法在高度多基因性特征方面表现出色,而其他方法在较少多基因性特征方面表现更好,这影响了跨祖先预测的准确性.

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