在瑞典接受注意力缺陷多动症 (ADHD) 治疗的儿童和成人的药物坚持:一项全国性研究
MaiBritt Giacobini1,2, Jingcheng Zhao3, Jonatan Freilich3,4
1PRIMA Järva, Spånga, Sweden.
Journal of attention disorders
|January 21, 2026
概括
总的来说,瑞典 (2015-2020年) 的ADHD兴奋剂治疗坚持率很高,特别是在成年人中. 然而,青少年对ADHD药物的坚持明显较低,这表明需要进一步调查.
科学领域:
- 药理学和治疗学 药理学和治疗学
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 注意缺陷/多动障碍 (ADHD) 是一种常见的神经发育障碍.
- 口服兴奋剂药物是儿童和成人ADHD的主要治疗方法.
- 了解治疗坚持对于优化治疗结果至关重要.
研究的目的:
- 为了确定瑞典口服兴奋剂ADHD药物的坚持率.
- 分析2015年至2020年期间不同年龄组 (儿童和成人) 的坚持模式.
主要方法:
- 一个回顾性,全国性的,基于登记的研究,使用瑞典处方药登记册.
- 包括服用口服兴奋剂的患者 (甲基胺,利斯胺,胺,安非他胺).
- 使用PDC方法计算治疗坚持率,采用修改后的每天一片药的方法.
主要成果:
- 从2015年到2020年,分析了超过158,000个治疗情节.
- 整体守率为78.2%,在甲基化物,利斯胺和胺类药物中具有相似的率.
- 在成年人 (69.3%-71.8%) 中观察到高坚持率 (≥80% PDC),但在青少年 (49.7%-52.4%) 中明显较低.
结论:
- 在瑞典人群中,口服兴奋剂ADHD药物坚持通常很高.
- 与成年人相比,青少年的坚持率较低,这表明在这个人口结构中存在潜在的挑战.
- 进一步的研究是有必要的,以探索原因和干预措施,以改善青少年的多动症药物坚持.
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