使用双光谱指数在睡眠内镜时麻醉深度的影响与PAP定位
Jefferson DeKloe1, Erin Creighton1,2, Jay Trivedi3
1Department of Otolaryngology, Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania, USA.
The Laryngoscope
|January 21, 2026
概括
麻醉深度会影响药物诱导睡眠内镜 (DISE) 期间的气道缩性. 在DISE-PAP期间的喉开口压力 (PhOP) 与双光谱指数 (BIS) 读数相关,表明其在评估气道阻力方面的实用性.
科学领域:
- 睡眠医学 睡眠医学
- 麻醉学 麻醉学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 药物诱导睡眠内镜 (DISE) 期间的气道缩受麻醉深度的影响.
- 双光谱指数 (BIS) 监测使用EEG信号量化麻醉深度.
研究的目的:
- 为了研究麻醉深度和气道缩性之间的关系,在DISE与正气道压力 (DISE-PAP) 期间.
- 在轻度和深度镇静水平下,评估VOTE得分和喉开口压力 (PhOP) 的变化.
主要方法:
- 一项前性研究涉及17名患有OSA的患者接受DISE-PAP.
- 使用BIS监测麻醉深度,轻度镇静被定义为BIS≥55和深度镇静为BIS<55.
- 在两个镇静水平下,PhOP被测量为开放气道所需的最低正气道压力.
主要成果:
- 喉开口压力 (PhOP) 与BIS读数呈现出显著的负相关性 (rho = -0.45,p = 0.0328).
- 毛皮和上衣的打开压力也与BIS水平相关 (p < 0.05).
- VOTE分类与BIS水平没有显著的相关性 (p = 0.189).
结论:
- 用BIS测量的麻醉深度与通过PhOP评估的呼吸道阻力相关.
- 阳性气道压力 (PAP) 是DISE中一个有价值的工具,用于立即和可定位的喉折叠性测量.
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