围产期风险因素和临床相关性在摩尔切割器低矿化:一个横截面的流行病学研究
Esztella-Éva Kis1, Ilona-Boglárka Gecse1, Cristina Bica1
1Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, Romania.
Epidemiologia (Basel, Switzerland)
|January 21, 2026
概括
摩尔切割器低矿化 (MIH) 与母亲的药物治疗和低出生体重有关. 婴儿期发烧性疾病可能会增加MIH儿童的牙过敏.
科学领域:
- 儿科牙科 儿科牙科
- 发育生物学 发展生物学
- 公共卫生 公共卫生
背景情况:
- 摩拉切割器低矿化 (MIH) 是一种发育性面膜缺陷,影响永久性摩拉和切割器.
- 系统性起源和围产期因素与MIH的发展有关.
- 生命第一年的发烧性疾病在一些MIH病例中显示出与过敏症的显著关联.
研究的目的:
- 为了研究围产期因素和切器低矿化 (MIH) 结果之间的关联.
- 确定与MIH相关的风险因素和保护因素.
- 分析母亲健康和早期儿童因素对MIH的影响.
主要方法:
- 对50名被诊断患有MIH的儿童的母亲进行了问卷调查.
- 数据分析包括千平方测试和后勤回归 (单变量和多变量).
- 临床诊断MIH遵循了欧洲儿科牙科学会 (EAPD) 的标准.
主要成果:
- 怀孕期间母亲的药物与早产相关.
- 低出生体重与牙喷发障碍和围产期并发症有显著的相关性.
- 化物应用显示出对MIH变色,皮和过敏的保护作用.
- 生命第一年的发烧性疾病独立地与MIH受影响的牙的过敏相关.
结论:
- 孕产妇服用药物和产周并发症,特别是低出生体重,与MIH发生有关.
- 预防策略应侧重于母亲健康和早期干预.
- 重矿化疗法可以帮助管理MIH患者的长期口腔健康问题.
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