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Updated: Jan 22, 2026

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach
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实验性和in-silico方法研究碳氧化酶基质的特异性

Sergio R Ribone1, Mario Alfredo Quevedo1

  • 1Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Ciencias Farmacéuticas, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba X5000HUA, Argentina.

Journal of xenobiotics
|January 21, 2026
PubMed
概括

人类的碳氧化酶 (CES) 是药物代谢中的关键酶. 通过结合实验和计算方法了解CES1和CES2基质特异性,可以优化药物设计和生物激活策略.

关键词:
CES1 关于我们的生活在CES2上,你会看到CES2.在HPLC中使用HPLC.在 LC/MS 中使用.模拟MD的模拟方法QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM QM/MM碳氧基乙酶是一种碳氧基乙酶.停靠的对接方式选择性的选择性基板是一种基板.

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