老年人的心脏代谢指数,BMI,腰围和心脏代谢多病风险
Setor K Kunutsor1,2, Jari A Laukkanen3,4
1Section of Cardiology, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R2H 2A6, Canada.
Geriatrics (Basel, Switzerland)
|January 21, 2026
概括
心脏代谢指数 (CMI) 显示了与老年人心脏代谢多病症 (CMM) 风险的相关性. 然而,像身体质量指数 (BMI) 和腰围 (WC) 这样的传统措施对CMM显示出更强的预测效用.
科学领域:
- 老年学是一门学科.
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
背景情况:
- 心脏代谢指数 (CMI) 是评估心脏代谢风险的新兴人体代谢指标.
- 了解CMI与身体质量指数 (BMI) 和腰围 (WC) 等既定指标相比的预测价值对于识别患有心脏代谢多病症 (CMM) 风险的个体至关重要.
研究的目的:
- 为了比较CMI,BMI和WC在老年成人队列中发生心脏代谢多病症 (CMM) 的关联和预测效用.
- 评估CMI在超越传统风险因素的CMM预测中的附加值.
主要方法:
- 长度研究使用来自英国长度老龄化研究的3348名老年人 (平均年龄63.5岁) 的数据.
- 参与者在基线没有主要的心脏代谢疾病 (第4波).
- 通过使用甘油三与高密度胆固醇的比率和腰与身高的比率来计算CMI. 发生的CMM (≥2种疾病:高血压,心血管疾病,糖尿病,中风) 被评估了12-15年 (第10波).
主要成果:
- 较高的CMI,BMI和WC都与患CMM的风险增加有线相关.
- 腰围 (WC) 显示出与CMM风险的最强相关性.
- 虽然CMI改善了模型匹配,但与BMI和WC相比,它并没有显著提高CMM预测的歧视.
结论:
- 在英国老年人中,高CMI与长期患心脏代谢多病症的风险更高有关.
- 传统的脂肪测量措施,特别是腰围 (WC),在预测该人群中CMM方面似乎比CMI更有效.
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