素驱动乳腺癌的攻击性,通过激活NCOA1/STAT3通路而起作用

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Updated: Jan 22, 2026

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Khouloud Ayed1, Amal Gorrab1, Hichem Bouguerra1

  • 1Laboratory of Genetics, Immunology, and Human Pathologies, Department of Biology, Faculty of Sciences of Tunis, University Tunis El Manar, Tunis 2092, Tunisia.

Medical sciences (Basel, Switzerland)
|January 21, 2026
PubMed
概括

与肥胖相关的高丁水平通过激活LEPR/NCOA1/STAT3通路,驱动细胞增殖,迁移和上皮层-介质细胞过渡 (EMT) 来促进乳腺癌 (BC) 的攻击性. 这突出了与肥胖相关的BC.的潜在治疗目标.

关键词:
乳腺癌 乳腺癌 乳腺癌表皮 mesenchymal 过渡的转变.勒普丁是一种素.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖瘤的迁移 瘤的迁移

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