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Updated: Jan 22, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
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成年脊柱形手术中的表观遗传年龄与年代年龄:前性队列研究

Quante Singleton1,2, Rohit Bhan1,3, Yu Zhang4

  • 1Washington University School of Medicine in Saint Louis, Department of Orthopaedic Surgery.

Spine
|January 21, 2026
PubMed
概括

表观遗传年龄 (EA),生物衰老的衡量标准,与成人脊柱形手术中的术后并发症有关. 与时间学年龄相比,EA的增加预测了更高的不良结果风险,这表明EA是风险分层的潜在生物标志物.

关键词:
成年人的脊柱形生物衰老 生物衰老年代年代年代年代年代年代年代年代年代年代基因甲基化 DNA 甲基化表观遗传年龄 表观遗传年龄霍尔瓦特时钟的时间术后并发症 术后并发症风险分层是指风险的分层.软弱指数 (Frailty Index) 是一个脆弱指数.

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