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Updated: Jan 22, 2026

Derivation of Mouse Trophoblast Stem Cells from Blastocysts
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鼠标热原体干细胞缺乏TNFα激活的NFκB信号通路和炎症反应

Yeseul Bae1, Marwah Walid Ali Alzara1, Yan-Lin Guo1

  • 1Cell and Molecular Biology Program, University of Southern Mississippi, Hattiesburg, USA.

American journal of reproductive immunology (New York, N.Y. : 1989)
|January 21, 2026
PubMed
概括

热原体干细胞 (TSC) 不对TNFα作出反应,避免炎症诱导的细胞死亡. 这项研究揭示了这种不反应的分子基础,表明TSCs独立于TNFα信号传递来调节基本基因.

关键词:
NFκB的目标基因是NFκB的目标基因.这就是TNFα信号传递.细胞因子细胞毒性炎症反应是一种炎症反应.热囊细胞干细胞的干细胞

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