宫外妊娠的流行病学:全球负担和预测
Wei Li1, Wei-Feng Shen2, Yi-Li Gu3
1Department of clinical laboratory, The Affiliated Hospital of Jiaxing University, Jiaxing, China.
International journal of surgery (London, England)
|January 21, 2026
概括
异胎妊娠发生率在全球范围内正在下降,但死亡和残疾调整寿命年 (DALYs) 正在上升,特别是在社会人口统计指数较低的地区. 有针对性的生殖健康政策对于解决这些日益严重的不平等至关重要.
科学领域:
- 生殖健康 生殖健康
- 全球卫生流行病学
- 孕产妇的死亡率 孕产妇的死亡率
背景情况:
- 宫外妊娠 (EP) 是早期怀孕死亡率的重要因素.
- 全球趋势和EP的健康差异尚未得到充分理解.
研究的目的:
- 分析全球,区域和国家流行病学趋势以及从1990年到2021年间异胎妊娠的负担.
- 评估到2036年的子宫外妊娠负担的未来预测.
- 为了确定不同社会人口统计指数 (SDI) 级别的异胎妊娠负担的差异.
主要方法:
- 利用了2021年全球疾病负担研究 (GBD 2021) 的数据.
- 雇员的结合点回归,边界,健康不平等和分解分析.
- 绘制了长度趋势和预计的未来负担,直到2036年.
主要成果:
- 在1990年至2021年期间,EP的全球年龄标准化发病率 (ASIR) 降低了0.91%.
- 年龄标准化死亡率 (ASMR) 和残疾调整寿命年率 (ASDR) 保持稳定,但死亡人数和DALY分别增加了38.96%和37.75%.
- 在SDI较低的地区,特别是撒哈拉以南非洲地区,负担最大,但存在显著的不平等现象.
结论:
- 尽管发生率下降,但异胎妊娠导致死亡率和DALY增加,不成比例地影响SDI较低的地区.
- 扩大健康不平等需要有针对性的生殖健康政策.
- 改善孕产妇的结果需要在脆弱地区进行有针对性的干预.
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