变性人群中的发生率和严重程度
Courtney A Smith1, Oumaima Kaabi2, Amita K Manatunga3
1Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
JAMA dermatology
|January 21, 2026
概括
变性人,特别是那些接受激素治疗的人,经历了明显的发病率模式. 丸激素的跨男性个体表现出更高的风险,而雌激醇的变女性个体也可能发展.
科学领域:
- 皮肤病学和内分泌学
- 跨性别者健康研究研究
- 人口健康研究 人口健康研究
背景情况:
- 对于接受性别肯定激素治疗 (GAHT) 的跨性别个人来说是一个常见的担忧.
- 关于接受GAHT的跨性别人口中发病率的有限的人口级数据存在.
- 了解这些模式对于全面的跨性别医疗保健至关重要.
研究的目的:
- 为了比较跨性别个体的发病率,包括那些在GAHT,与匹配的 cisgender 个体.
- 评估这些群体中中度至重度的发病率.
- 分析基于跨性别身份的治疗利用率.
主要方法:
- 追溯匹配的队列研究,使用来自凯泽永久的电子健康记录数据.
- 包括没有基线的个体,变性男性和变性女性的个体与 cisgender 对照匹配.
- 长达5年的后续调查;分析是在2024年11月至2025年11月之间进行的.
主要成果:
- 累计5年发病率在变性男性中为15.8%,而 cisgender男性为3.8%, cisgender女性为10.5%.
- 变性男性的风险在开始后的第一年是最高的 (HR 8.29与 cisgender 男人相比).
- 与 cisgender男性相比,变性女性个体的风险在雌激素启动后较高 (HR 1.56),但低于 cisgender女性 (HR 0.53).
结论:
- 跨性别和 cisgender 个体之间存在明显的发病率模式.
- 对于开始使用丸激素的跨男性个体,建议密切监测和治疗,特别是在第一年内.
- 临床医生应该意识到,在开始雌激素治疗的转女性患者中,可能会出现.
相关概念视频
01:08Prevalence and Incidence
1.6K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.6K
01:21Types of Reports II: Incident or Occurrence Report
1.2K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
01:30Impact of Individuals on Individuals
361
Human behavior is intricately shaped by social influences that arise from interactions with others in diverse contexts. These influences not only mold beliefs and attitudes but also drive the regulation of behaviors through both direct communication and observational learning. The study of these processes falls within the domain of social psychology, which seeks to understand how individuals are affected by and affect those around them.Mechanisms of Social InfluenceDirect social influence...
361
01:28Impact of Groups on Individuals
318
Groups play a fundamental role in shaping individual behavior, as they establish norms that guide interactions and decision-making. Social psychology examines how individuals conform to group expectations, often adjusting their attitudes and actions to align with group norms. These norms can be formal, such as workplace policies, or informal, such as unspoken social expectations within a fraternity.Conformity and Social InfluenceConformity arises when individuals modify their behaviors or...
318
01:25Impact of Individuals on a Group
301
In social psychology, the interplay between individuals and groups is a central concern, particularly regarding how individual actions and characteristics influence group processes and outcomes. While much research emphasizes the group's power in shaping individual behavior, it is equally significant to understand how individuals contribute to the functioning, development, and success of groups.Individual Roles in Group Productivity and Decision-MakingIndividuals are not passive participants in...
301
01:28Adler's Individual Psychology
2.3K
Alfred Adler, a prominent figure in psychology, founded the school of individual psychology. In contrast to Freud's emphasis on sexual or aggressive motives, Adler suggested that individuals are primarily motivated by their purposes and goals. He believed that people strive for perfection rather than pleasure. Adler argued that individuals could creatively act upon their genetic inheritance and environmental experiences to shape their own lives, emphasizing conscious motivation over...
2.3K