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Updated: Jan 22, 2026

Author Spotlight: Investigating the Potential of Chinese Herbal Medicinal Active Dioscin in Treating IgA Nephropathy
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CFHR3*B哈普洛型,补充激活,以及IgA脏病的风险

Yongji Zhang1, Honghong Zou1,2, Xinran Ni1

  • 1Renal Division, Department of Medicine, Peking University First Hospital; Peking University Institute of Nephrology; Key Laboratory of Renal Disease (Peking University), National Health Commission; Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Ministry of Education; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University and NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides; Beijing, 100034, China.

Journal of the American Society of Nephrology : JASN
|January 21, 2026
PubMed
概括

该CFHR3*B单元型通过增强补体激活,增加IgA脏病的风险. 这种变异提高了与H因子相关的蛋白3 (FHR3) 的水平和功能,促进了疾病的进展.

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