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Updated: Jan 23, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
10:35

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

Published on: November 28, 2010

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活体免疫瘤学平台揭示了与ATR抑制反应相关的空间T细胞透模式,用于高度的严重卵巢癌

Ashwini Sakrepatna Nagaraj1, Matilda Salko1, Aditi Sirsikar1

  • 1University of Helsinki Helsinki Finland.

Cancer immunology research
|January 21, 2026
PubMed
概括

我们开发了免疫能力强的患者衍生培养物 (iPDCs) 来模拟高度血清性卵巢癌 (HGSC). 该平台确定了ATR抑制剂和Autotaxin免疫疗法的新组合疗法,用于HGSC治疗.

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Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
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