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Updated: Jan 23, 2026

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管理涉及非处方阿片类药物洛佩拉米德的药物相互作用,通过基于生理学的药物动力学建模

Zhu Zhou1, Garrett R Ainslie2, Mengyao Li3

  • 1Department of Chemistry, York College, City University of New York, Jamaica (Queens), New York, USA.

CPT: pharmacometrics & systems pharmacology
|January 21, 2026
PubMed
概括

一个新的模型预测了洛佩拉米德如何与其他药物相互作用. 这有助于防止洛佩拉米德的危险副作用,特别是与CYP或P-gp抑制剂结合使用时.

关键词:
PBPKK PBPK 的意思是什么意思这是一种P-glycoprotein蛋白.细胞染色体P450的使用.药物 药物相互作用抑制抑制抑制的抑制作用洛佩拉米德是什么意思 洛佩拉米德是什么意思这是一种阿片类阿片类药物.

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