非白人患者炎症性肠病中的肠外皮肤表现:一项回顾性多中心研究
Shaina Ailawadi1, Sahil Sethi1, Abdullah Mahmood1
1Departments of Internal Medicine.
炎症性肠病 (IBD) 患者的皮肤颜色显示较高的hidradenitis suppurativa和白风的比率. 在非白人IBD患者中识别这些皮肤表现 (CM) 对于更好的护理至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 胃肠病学 胃肠病学
- 健康差异 在健康上的差异
背景情况:
- 皮肤表现 (CM) 在炎症性肠病 (IBD) 中很常见,但研究主要集中在白人群体上.
- 在种族和少数民族中,IBD的患病率正在上升,这凸显了在不同肤色中了解CM的差距.
研究的目的:
- 调查与白色IBD患者相比,非白色IBD患者中各种CM的患病率和相关性.
- 解决不同人群中IBD相关皮肤病数据不足的问题.
主要方法:
- 利用医疗保健数据库来识别被诊断患有IBD的白人和非白人患者.
- 包括处方IBD特异性药物或先进疗法的患者.
- 员工倾向性得分匹配用于队列比较.
主要成果:
- 在白人和非白人队列中确定了35,624名匹配患者.
- 非白人IBD患者患上腹炎的几率增加了2倍以上,白风的几率增加了2倍以上.
- 在非白人患者中观察到牛皮,疹和白细胞结晶性血管炎的相关性减少;在其他疾病中没有差异.
结论:
- 在非白人IBD人群中,CM存在显著的不足和不足.
- 研究结果表明,非白人IBD患者的特定CM患病率增加.
- 在这些患者中更好地识别CM可以改善生活质量并降低发病率.
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