通过多策略非目标选在中国城市河流系统中发现被忽视的化化合物
Xuebing Wang1, Jiaqi Yang1, Zhaoyu Jiao1
1State Key Laboratory of Water Pollution Control and Green Resource Recycling, School of Environment, Nanjing University, Nanjing 210023, People's Republic of China.
Environmental science & technology
|January 21, 2026
概括
一个新的选框架在阳河中确定了106种化化合物,包括36种和多基物质 (PFAS). 该方法揭示了许多以前未报告的化学物质,改善了对这些物质的环境监测.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 环境科学 环境科学
背景情况:
- 和多醇基物质 (PFAS) 是越来越令人担忧的环境污染物.
- 目前的监测方法只能检测到有限范围的化化合物.
- 了解化化合物污染的全部范围对于有效的环境管理至关重要.
研究的目的:
- 开发和验证一个全面的非目标查框架,用于识别环境样本中的各种化化合物.
- 评估化物化合物的化学多样性在阳河,一个代表性的城市流域.
- 发现以前未报告的化化学品及其转化产品.
主要方法:
- 开发一个多策略的非目标查框架,利用7096种化化合物的高分辨率MS/MS库.
- 集成目标分析,数据库匹配,同类选,分子网络和基于反应库的注释.
- 该框架应用于中国阳河的水样.
主要成果:
- 在阳河中鉴定了106种化化合物.
- 确认和量化36个per-和多基基物质 (PFAS),揭示了时空趋势.
- 发现了23种以前未报告的化合物,包括新型甲乙烯碳酸酸类和化芳香中间体,以及各种转化产品.
结论:
- 开发的多策略非目标查框架有效地扩大了检测能力,超出了目前的监测限制.
- 这项研究突出了现有的多基化合物 (PFAS) 监测协议中的重要盲点.
- 这种方法对于全面了解和管理城市水生环境中化合物污染至关重要.
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