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Updated: Jan 23, 2026

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
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Published on: June 30, 2021

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通过P2RX7对细胞外ATP的调节性T细胞感知促进其积累和抑制,并驱动肺瘤的生长

Igor Santiago-Carvalho1, Ronaldo Francisco2, Bruna de Gois Macedo3

  • 1Mayo Clinic Phoenix, Arizona United States.

Cancer immunology research
|January 21, 2026
PubMed
概括

调控性T细胞 (Tregs) 在肺癌中抑制抗瘤免疫力. Tregs上的P2RX7受体增强了这种抑制,促进了瘤的生长. 阻断P2RX7可能通过减少免疫抑制来改善肺癌治疗.

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