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Updated: Jan 23, 2026

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
07:57

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发现了二[2,3-b][1,4]氨酸-2(3H) - 一种STING抑制剂

Lu Han1, Shumin Zang2, Wenxin Li3

  • 1School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, PR China.

Bioorganic & medicinal chemistry
|January 21, 2026
PubMed
概括

研究人员发现了一种新型的thieno[2,3-b][1,4]thiazin-2(3H) -one STING抑制剂. 化合物11h在体外和体内有效地抑制了STING信号传递,为治疗炎症性干扰性病变提供了潜力.

关键词:
抗炎药物 抗炎药物 抗炎药物作为刺痛的抑制剂.干扰素是干扰素的一种.提[2,3-b][1,4]提亚是一种

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