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Enterococcus faecalis通过调节头微生物群和肠道屏障来增强的生长和免疫力
Yizhe Cui1, Mengmeng Liu1, Lei Liu1
1Key Laboratory of Exploration and Innovative Utilization of White Goose Germplasm Resources in the Cold Region of Heilongjiang Province, College of Animal Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang 163319, China.
Poultry science
|January 21, 2026
概括
Enterococcus faecalis补充剂通过增强免疫力,肠道屏障功能和有益的肠道细菌来改善的生长. 这种益生菌料添加剂显示出提高家禽生产效率的巨大潜力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 在养中,Enterococcus faecalis (E. faecalis) 越来越多地被用于养,因为它的好处.
- 它在减少腹,抑制大肠杆菌,改善生产和料利用方面表现出有效性.
研究的目的:
- 研究E. faecalis对齐生长,免疫力,肠道屏障和直肠微生物群的影响和机制.
- 利用网络药理学和动物实验来探索这些影响.
主要方法:
- 网络药理学预测了与附着结和IgA生产相关的途径.
- 齐补充了E. faecalis (1 × 108 CFU/mL) 在饮用水中,持续48天.
- 评估了生长表现,血清免疫标记物,阴茎形态,基因表达和阴茎微生物群组成.
主要成果:
- E. faecalis 补充剂显著提高了最终体重,料摄入量和每日增加 (P < 0.05).
- 观察到血清IgA (P < 0.01) 和IgG (P < 0.05) 水平升高.
- 改善了阴形态 (增加了的高度,减少了密室深度),调高了紧结基因表达 (Claudin-1,ZO-1) 和sIgA,并调低了IFNG表达 (P <0.05).
- 杰的微生物群发生了转变,蛋白质菌减少,菌菌和动菌菌增加,与改善的生理指数相关 (P < 0.05).
结论:
- 补充Enterococcus faecalis可以提高的生长性能.
- 机制包括改善免疫力,加强肠道屏障功能和优化微生物平衡.
- E. faecalis在生产中显示出作为益生菌料添加剂的巨大潜力.
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