整体喉腔切除术后发病不消化症的危险因素
Brooke Swain1, Clara D Si1, Daniel R S Habib1
1Vanderbilt University School of Medicine, Nashville, TN, USA.
American journal of otolaryngology
|January 21, 2026
概括
在全喉切除术 (TL) 后,缺是常见的. 之前的辐射,辅助辐射,喉切除术和舌头底部切除术增加了失消症的风险. 拯救TL患者需要就潜在的食道扩张进行咨询.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 头部和部手术 头部和部手术
- 手术瘤学手术瘤学
背景情况:
- 整体喉切除术 (TL) 后的严重并发症是缺,严重影响患者的生活质量.
- 许多接受TL的患者需要重复的食道扩张来管理吞困难.
- 识别TL后食障碍的危险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定手术和非手术风险因素,与整体喉切除术后的消化不良相关.
- 分析导致临床诊断的消化不良和需要食道扩张的消化不良的因素.
主要方法:
- 在1999年至2024年期间接受了TL的787名患者的回顾性队列研究.
- 评估的结果包括临床诊断的消化不良和需要食道扩张的消化不良.
- 后勤回归分析被用来评估食障碍与辐射,BMI和外科手术等共变量之间的关联.
主要成果:
- 26.9%的患者报告患有食障碍,16.6%的患者需要食道扩张.
- 之前的辐射 (aOR: 2.51),辅助辐射 (aOR: 1.86) 和舌头底部切除 (aOR: 2.14) 独立地与临床食症相关.
- 之前的辐射是唯一独立与需要扩张的消化不良症相关的因素 (aOR:2.92).
结论:
- 缺是全喉切除术的重要和常见的后果.
- 诸如先前辐射,辅助辐射,全喉切除术,舌头底部切除术和脚踏重建等因素影响吞结果.
- 接受救援TL的患者应被告知可能需要进行喉切除术后食道扩张.
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